buy BATRACHOTOXIN Phyllobates online

Description

buy BATRACHOTOXIN Phyllobates online
Name BATRACHOTOXIN
Molecular formula C31H42N2O6
Description The strongest sodium channel activator so far
Alkaloid with a steroid skeleton, an oxazapine ring and a dimethylpyrrole carboxylate moiety , purified from skin extract of the poison dart frog Phyllobates terribilis
Biological activity BTX is the most active alkaloid binding at receptor site-2 on sodium channels. It activates the sodium channel even at very negative membrane potentials and keeps it open permanently by preventing channel inactivation. BTX also changes the selectivity of the channel to Na+ ions and makes it less selective, enabling larger ions to pass through the pore. EC50 (in vitro): 0.1 to 100 nanomolar.
BTX binding induces many allosteric effects on other channel regions, and increases the binding of scorpionalpha-toxins to receptor site-3, of Brevetoxin to receptor site-5, and of pyrethroid insecticides to receptor site-7.
Research tool applicable to the study of the function of sodium channel and the effects of other toxins and of a variety of drugs, including anesthetics, analgesics, antiarrhythmics, anticonvulsants and antidepressants.BATRACHOTOXIN from Phyllobates terribilis The strongest sodium channel activator so far. Batrachotoxin is an alkaloid purified from skin extract of the poison dart frog Phyllobates terribilis.
High chem is the world exclusive source of this toxin.
Molecular formula: C31H42N2O6
Chemical structure: Click on the picture on the left.
Molecular weight : 538.67 Da
Purity : > 90%
Biological Activity :
Batrachotoxin is a Na+ channels activator.
Batrachotoxin (BTX) is the most active alkaloid binding at receptor site-2 on sodium channels.
BTX activates the sodium channel even at very negative membrane potentials and keeps it open permanently by preventing channel inactivation.

buy BATRACHOTOXIN Phyllobates online

BTX also changes the selectivity of the channel to Na+ ions and makes it less selective, enabling larger ions to pass through the pore. EC50 (in vitro): 0.1 to 100 nanomolar.BTX binding induces many allosteric effects on other channel regions and increases the binding of scorpion alpha-toxins to receptor site-3, of brevetoxin to receptor site-5, and of pyrethroid insecticides to receptor site-7.
Batrachotoxin-sensitive sodium channels are expressed in central and peripheral neurons and in both striated and cardiac muscle, where they regulate excitability.
BTX is used for the study of the function of sodium channels.
BTX is used for the study of the effects of other toxins and of different kinds of drugs (anesthetics, analgesics, antiarrhythmics, anticonvulsants, and antidepressants). Recommended doses: < 1 µg/kg. Batrachotoxin toxicity Phyllobates terribilis toxin What is Batrachotoxin? Phyllobates frogs Batrachotoxin effects on humans Batrachotoxin mechanism of action Phyllobates poison Batrachotoxin vs other toxins Phyllobates terribilis habitat Batrachotoxin and cardiac effects Batrachotoxin lethal dose Phyllobates frogs and their toxins Phyllobates terribilis venom Phyllobates toxins and evolution Batrachotoxin research Phyllobates terribilis care in captivity How Batrachotoxin works Batrachotoxin and nerve receptors Batrachotoxin as a weapon Batrachotoxin and sodium channels Batrachotoxin frog species Phyllobates terribilis danger Batrachotoxin frog toxicity in nature Can humans survive Batrachotoxin poisoning? Batrachotoxin and medicinal research Batrachotoxin: The Lethal Toxin of Phyllobates Frogs Introduction to Batrachotoxin Batrachotoxin is one of the most potent and lethal toxins known to science. This powerful toxin is primarily found in the Phyllobates genus of frogs, particularly the Phyllobates terribilis, also known as the golden poison dart frog. It is a neurotoxin that can cause severe physiological effects, even in small quantities. In this article, we'll explore what Batrachotoxin is, how it works, its effects on the human body, and the frogs that produce it.